Search on: APC1 SUBUNIT, ANAPHASE-PROMOTING COMPLEX 
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Descriptor English:   Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome 
Descriptor Spanish:   subunidad Apc1 del complejo promotor de la anafase-ciclosoma 
Descriptor Portuguese:   Subunidade Apc1 do Ciclossomo-Complexo Promotor de Anáfase 
Synonyms English:   Anapc1
Apc1 Subunit, Anaphase Promoting Complex
Apc1 Subunit, Anaphase Promoting Complex Cyclosome
Apc1 Subunit, Anaphase-Promoting Complex  
Tree Number:   D08.811.464.938.750.092.500
D12.776.167.024.500
Definition English:   The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55273 
Unique Identifier:   D064189 

Occurrence in VHL:
 

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